Taking a commonly prescribed class of antibiotics may DOUBLE your chances of getting a ‘leaky valve’ which leads to heart failure, study claims
Fluoroquinolone antibiotics commonly used to treat chest infections and UTIs
GPs prescribe over 600,000 each year and like fact they tackle range of bacteria
US researchers have found they double chance of potentially deadly leaky valve
Taking a common class of antibiotics may more than double your chances of getting a serious heart condition, a study suggests.
Researchers found patients using fluoroquinolones had a greater risk of developing aortic and mitral regurgitation, which can lead to heart failure.
The drugs are commonly used to treat everything from chest infections to urinary tract bugs.
Ciprofloxacin is the most prescribed of these, but other types include levofloxacin, moxifloxacin and norfloxacin.
Researchers at the University of British Columbia (UBC) looked at 125,020 patients who’d taken antibiotics in the last year.
Some had been prescribed fluoroquinolones while others had taken amoxicillin or azithromycin – other types of antibiotics.
The research team discovered 12,505 cases of a leaky valve, which can affect how blood flows around the body.
They found current fluoroquinolone users were 2.4 times more likely to develop the condition than those on amoxicillin.
Meanwhile, patients on fluoroquinolone were at a 1.8 times greater risk than those using azithromycin.
WHAT IS A LEAKY MITRAL VALVE?
The mitral valve is a small flap in the heart that stops blood flowing the wrong way. If damaged, it can affect how blood flows around the body.
A ‘leaky’ mitral valve is the nickname for a condition called mitral regurgitation, when it doesn’t close tightly enough and blood goes the wrong way.
This puts a strain on the heart and often causes symptoms such as breathlessness and fatigue, Harvard Medical School states.
In the long-run, mitral regurgitation can lead to serious complications such as atrial fibrillation (an irregular heartbeat) and heart failure.
It is often caused by mitral valve prolapse, when the flaps – called leaflets – bulge back into the left atrium as the heart contracts.
However, a leaky mitral valve also can happen with age, through general ‘wear and tear’ of the valve, the NHS says.
Other causes include cardiomyopathy (stiff heart chamber muscles), an infection of the inner lining of the heart, or congenital heart disease.
Statistics suggest the NHS undertakes around 2,200 mitral valve repair operations each year.
Those who had come off fluoroquinolone within the last 60 days were 1.5 times more likely …read more
Source:: Daily Times